Sibutramine Raw MaterialCAS106650-56-0

CAS number: 106650-56-0
Molecular formula: C17H26ClN
Molecular weight: 279.85
Accurate quality: 279.17500
PSA：3.24000
LogP：4.73800
Physical and chemical properties
Appearance: White crystalline powder
Melting point: 191-192 ° C
Molecular structure data
1. Molar refractive index: 83.76
2. Molar volume (cm3/mol): 271.3
3. Waiting for Zhang Biarong (90.2K): 670.5
4. Surface tension (dyne/cm): 373.3
5. Polarization rate (10-24cm3): 33.2
6. Single isotope mass: 279.175378 Da
7. Nominal mass: 279 Da
8. Average quality: 279.848 Da
Calculate chemical data
1. Reference value for hydrophobic parameter calculation (XlogP): 5.4
2. Number of hydrogen bond donors: 0
3. Number of hydrogen bond acceptors: 1
4. Number of rotatable chemical bonds: 5
5. Number of tautomers: 0
6. Topological molecular polarity surface area: 3.2
7. Number of heavy atoms: 19
8. Surface charge: 0
9. Complexity: 275
10. Number of isotopic atoms: 0
11. Determine the number of atomic stereocenters: 0
12. Uncertain number of atomic stereocenters: 1
13. Determine the number of chemical bond stereocenters: 0
14. Number of uncertain chemical bond stereocenters: 0
15. Number of covalent bond units: 1

Sibutramine raw material is used as a medicinal material for weight intervention, with the core function of regulating the levels of central neurotransmitters in the human body. By inhibiting the reuptake of norepinephrine, serotonin, and dopamine, it increases the concentration of satiety signals in the body, effectively enhances the feeling of fullness and weakens hunger, and reduces the desire and amount of food intake from the source. At the same time, this raw material can gently activate the body's metabolic heat production mechanism, increase basal energy consumption, accelerate the metabolism of excess calories in the body, and have a dual effect to assist in weight control. It has a fast onset of action and significant effects, and has been suitable for weight adjustment in overweight and obese populations. This ingredient only acts on the neural metabolic regulation pathway and has no physical filling effect. It has outstanding efficiency in reducing fat and weight, and has been a clear active ingredient in clinical weight loss applications.

This substance can regulate the levels of central nervous system neurotransmitters in the human body, enhance satiety perception, increase energy consumption, and is used for the development of obesity drugs. At present, this product is only used as a raw material for scientific research experiments, exclusively for laboratory pharmacological analysis, drug structure research, and new drug development. It cannot be added to food, dietary supplements, and other products. It is prohibited to directly apply it to the human body. All circulation and use strictly follow relevant regulatory regulations. Strictly abide by the relevant laws and regulations of national drug supervision.

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