Avermectin Powder CAS 71751-41-6

Avermectin Powder CAS 71751-41-6

Avermectin Powder CAS 71751-41-6 is a natural fermentation-based veterinary antiparasitic API belonging to the macrolide family. Different from chemically synthesized anthelmintic raw materials such as albendazole, avermectin is produced through microbial deep fermentation, featuring natural pharmacological activity, broad parasite-killing spectrum and good environmental compatibility. It is a widely used core raw material for internal and external parasite control formulations in the global animal health industry, extensively applied in livestock breeding, poultry farming, aquaculture and commercial animal parasite prevention scenarios.

Product Introduction

Through long-term cooperation with global veterinary formulation manufacturers, feed additive processors and aquaculture drug enterprises, we have summarized typical B2B procurement pain points for fermented antiparasitic APIs. Most generic avermectin powder available on the market features unstable fermentation component ratios, high soluble impurity content, obvious batch color deviation, poor powder fluidity and unqualified solvent residues. These common defects easily cause inconsistent finished drug efficacy, turbid liquid formulations, failed third-party sampling tests and delayed overseas product registration progress. As a professional manufacturer specialized in microbial fermentation veterinary APIs, we optimize strain cultivation, fermentation metabolism and post-purification procedures to solve practical industrial problems, providing stable, formulation-compatible Avermectin Powder CAS 71751-41-6 for global B2B buyers.

 

Standard Product Specifications

 

All technical parameters strictly comply with international veterinary industry standards and fermentation API production norms, with complete batch detection data to ensure verifiable and stable quality:

Product Name Avermectin Powder
CAS Number 71751-41-6
Molecular Formula C₄₈H₇₂O₁₄
Molecular Weight 872.08
Appearance White to pale yellow crystalline powder
Grade Veterinary Fermentation API Grade
Total Purity (HPLC) ≥95.0%
Main Active Component Controlled and consistent B1a/B1b fermentation proportion
Solubility Soluble in conventional organic solvents, slightly soluble in water; stable dissolution state for spray, pour-on and oral formulations
Loss on Drying ≤1.0%
Residue on Ignition ≤0.2%
Solvent Residue Compliant with international veterinary API export standards
Storage Conditions Sealed, light-proof, low-temperature dry storage, away from high temperature and humid environment
Shelf Life 24 months under standard sealed storage conditions

 

Antiparasitic Mechanism & Product Characteristics

 

Avermectin exerts stable antiparasitic effects by interfering with parasite neuroelectrical conduction. It specifically binds to glutamate-gated chloride channels of invertebrate parasites, blocking normal nerve signal transmission and triggering parasite paralysis and death. This targeted working mechanism only affects invertebrate parasites, bringing negligible interference to nerve systems of mammals and aquatic organisms, ensuring high safety for animal medication and conventional breeding environments.

Distinct from benzimidazole chemical anthelmintics that only target internal parasites, avermectin delivers dual effects on internal nematodes and external arthropod parasites. It effectively controls common swine and cattle gastrointestinal nematodes, poultry respiratory parasites, animal body lice, mites and ticks, as well as various ectoparasites affecting aquatic animals. Its broad-spectrum parasiticidal property makes it a practical raw material for comprehensive deworming and regular parasite prevention in large-scale breeding bases. Meanwhile, due to its natural fermentation source, avermectin features low drug residue and low tendency of drug resistance development, suitable for long-term cyclic medication in standardized breeding systems.

 

Core Factory Manufacturing Advantages

1. Stable Fermentation Process & Consistent Batch Quality

The core quality difficulty of avermectin API lies in the stability of microbial fermentation process. Many small factories adopt unstable strain activation and fermentation culture technology, resulting in fluctuating active component content, inconsistent color and uneven efficacy between batches. Our factory applies fixed high-quality strain banks, standardized temperature and oxygen control fermentation systems, and staged metabolic regulation technology. The whole fermentation process is digitally monitored, and post-purification and crystallization processes are strictly controlled to ensure consistent active component ratio, stable purity indicators and unified powder appearance in each batch, minimizing finished product efficacy deviation caused by raw material batch differences.

2. Strict Purification & Low Residue Control System

Fermentation-derived APIs are prone to microbial impurities, protein residues and solvent residues, which will cause solution turbidity, precipitate generation and unqualified residue detection of downstream finished preparations. We adopt multi-stage membrane filtration, high-precision recrystallization and vacuum drying processes to effectively remove macromolecular impurities and residual solvents. Each batch is tested by HPLC and residual solvent detection equipment to strictly control impurity content, ensuring that the raw materials meet the production requirements of qualified standard liquid solutions, external spray agents and pour-on preparations, helping customers pass local market sampling inspections smoothly.

3. Physical Property Customization for Diversified Formulation Needs

Different downstream formulation scenarios have distinct requirements for avermectin powder physical properties. External spray and liquid formulations require fine particle size and excellent dispersion performance; feed premix production demands stable powder fluidity to avoid agglomeration and component stratification; high-purity compound formulations require low impurity and stable active ingredient content. Based on years of fermentation production and formula matching experience, we can adjust powder fineness, particle size distribution and bulk density within industry standard ranges according to customers' production processes, simplifying customers' secondary processing and improving finished product qualification rates.

4. Complete Qualification Documents for Global Market Access

Fermentation-grade veterinary API exports are subject to stricter overseas regulatory supervision compared with chemically synthesized raw materials, especially in production traceability and impurity control standards. As a direct fermentation manufacturer, we provide authentic, audit-able and complete document sets including batch COA, SDS, production qualification files, fermentation process records and impurity spectrum reports. All documents comply with international export standards, supporting customers' daily customs clearance and veterinary product registration in Southeast Asia, Africa, Latin America and other mainstream overseas markets, helping customers avoid market entry barriers caused by incomplete documentation.

5. Sufficient Capacity & Seasonal Stable Supply

Animal parasite prevention and control presents obvious seasonal demand fluctuations, which easily cause market supply shortages and price instability in peak seasons. We own dedicated avermectin fermentation workshops and independent purification production lines with steady annual output capacity. We maintain year-round conventional safety stock to cope with seasonal demand growth and raw material market fluctuations. We support laboratory sample testing, small-batch trial production and large-tonnage long-term framework cooperation orders, ensuring stable and on-time shipment for all customer orders throughout the year.

Professional Application Scope & Compliance Guidelines

 

Avermectin Powder CAS 71751-41-6 is a dedicated fermentation-grade veterinary antiparasitic API, widely used in the production of animal health and aquaculture disease prevention products, covering multiple breeding scenarios:

1

Livestock Parasite Prevention: Used for regular deworming of cattle, sheep, swine and other livestock, effectively removing internal nematodes and external mites, ticks and lice, supporting parasite control and reducing parasitic infection risks in breeding livestock

2

Poultry Antiparasitic Preparations: Applied in poultry oral medicines and external spray formulations for the prevention and auxiliary treatment of respiratory and digestive tract parasitic infections, assisting stable poultry growth and uniform breeding quality

3

Aquaculture Disease Control: Used for auxiliary prevention and treatment of common parasitic diseases in fish, shrimp and crab farming, effectively reducing breeding losses caused by parasitic infestation

4

Feed Additive Premix: Added into compound feed as a routine preventive deworming raw material, suitable for standardized intensive livestock and poultry breeding farms

5

Compound Antiparasitic Formulations: Compatible with multiple veterinary API ingredients to develop internal and external dual-effect deworming products, enriching customers' downstream animal health product lines

6

Compliance Reminder: This product is a professional veterinary-specific API raw material and is prohibited for human medical use. All finished products processed with this raw material must comply with local veterinary drug administration regulations, with strict adherence to official dosage specifications and drug withdrawal period requirements to prevent animal product residue risks.

Standard Packaging & Logistics Solution

 
 

Sample Packaging

1kg/5kg vacuum-sealed aluminum foil bag, light-proof and moisture-proof, with independent batch number and complete test report

 
 
 

Bulk Standard Packaging

25kg industrial fiber drum with double-layer PE inner sealed bag, meeting international export packaging standards

 
 
 

Customized Service

Support pallet packaging reinforcement, waterproof and shockproof treatment, and exclusive packaging customization according to customer logistics and storage needs

 

 

Practical Industry FAQ

 

Q1: What is the biggest difference between fermented avermectin and synthetic antiparasitic raw materials?

A: Avermectin adopts natural microbial fermentation technology with mild pharmacological properties, low residual level and low drug resistance development tendency. It provides dual antiparasitic effects against both internal and external parasites, while most chemically synthesized anthelmintic APIs only target internal parasites. It is highly adaptable for long-term cyclic parasite prevention and control in diversified livestock, poultry and aquaculture breeding scenarios.

Q2: Can you provide customized powder physical indicators?

A: Yes. We can adjust particle size, fineness and bulk density within standard ranges according to customers' liquid formulation, solid powder and feed premix production processes to match different downstream production equipment and formula systems.

Q3: How to ensure batch stability of fermented avermectin?

A: We adopt fixed strain banks, standardized fermentation parameter settings and unified post-purification processes. Each production batch is equipped with complete HPLC detection data and impurity analysis reports, ensuring stable active ingredient content and consistent overall quality between different batches.

Q4: What delivery and payment terms can be supported?

A: Conventional in-stock specifications can be delivered within 7–10 working days. We support mainstream international payment methods including T/T and sight L/C. Long-term stable cooperative customers can negotiate flexible settlement terms and priority shipment arrangements.

Q5: What is your after-sales quality guarantee policy?

A: All products are delivered with official factory inspection documents. Customers can arrange third-party quality testing via authoritative institutions. If verified quality issues occur due to our production negligence, we will provide replacement, re-production or refund services strictly in accordance with formal contract terms.

 

Inquiry & Long-Term Factory Cooperation

 

If you are searching for a stable and reliable factory supplier of Avermectin Powder CAS 71751-41-6 fermentation veterinary antiparasitic API, please feel free to send your required quantity, customized specification demands, application scenarios and document requirements. Our professional sales and technical team will provide targeted product solutions and accurate factory ex-factory quotations within 24 hours. We insist on stable quality and reliable long-term supply, and welcome global veterinary pharmaceutical manufacturers, feed additive enterprises and aquaculture drug distributors to establish mutually beneficial and stable cooperative partnerships.

 

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