High-Quality Glabridin Raw Material

Glabridin (CAS No. 59870-68-7) is a flavonoid compound extracted from the roots of Glycyrrhiza glabra (licorice). Its molecular formula is C20H20O4, and its molecular weight is 324.3704. Glabridin inhibits tyrosinase activity, thereby reducing melanin production. It accounts for only 0.08%–0.35% of the dry weight of licorice roots, making extraction particularly challenging. For this reason, it is often referred to as "liquid gold" in skin-whitening applications.

Glabridin also exhibits antioxidant and anti-inflammatory properties. Its antioxidant capacity is comparable to that of vitamin E, making it a potential natural antioxidant ingredient.

In the cosmetics industry, Glabridin is widely used to help inhibit UV-induced pigmentation. In pharmaceutical applications, it is used for its potential to protect against free radical-induced damage, help prevent atherosclerosis, and support blood lipid reduction.

Commercial raw materials are commonly supplied in the form of oil-soluble licorice extract containing 40% Glabridin.

Glabridin is one of the major flavonoid constituents of Glycyrrhiza glabra. It demonstrates potent free radical scavenging and antioxidant activity in the cytochrome P450/NADPH oxidation system. It can significantly inhibit free radicals generated during metabolic processes in the body, thereby protecting oxidation-sensitive biomolecules, such as low-density lipoprotein (LDL) and DNA, as well as cell membranes, from oxidative damage caused by free radicals.

These properties may help prevent or mitigate certain pathological conditions associated with oxidative stress, including atherosclerosis and cellular aging.

In addition, Glabridin exhibits certain lipid-lowering and blood pressure-lowering effects. Research conducted in Italy has also reported that Glabridin may help suppress appetite and reduce body fat without reducing overall body weight.

Repeated experimental evaluations have identified the following primary functional properties:

● Skin brightening and inhibition of melanin production

● Anti-inflammatory activity

● Antioxidant activity

● Antibacterial activity

1. Skin-brightening and spot-correcting serums, brightening concentrates, ampoules, and other functional liquid formulations.

2. Repair masks, rubber masks, and professional skincare products designed to improve redness and pigmentation.

3. Skin-brightening lotions, face creams, and tone-up creams for long-term improvement in skin tone uniformity.

4. After-sun repair products designed to help protect against UV-induced irritation and prevent tanning.

5. Gentle skin-brightening skincare products specifically formulated for sensitive skin.

6. Multi-ingredient skin-brightening formulations, commonly combined with tranexamic acid, alpha-arbutin, and glutathione.

1. 40% Grade: Entry-level mainstream specification; brownish-yellow powder with excellent cost-effectiveness. Assay determined by HPLC.

2. 90% Grade: Mid-to-high-end specification; off-white powder with a low impurity profile. Commonly used in the commercial market.

3. 98%/99% Grades: High-purity specifications; white crystalline powder, suitable for premium functional formulations and reference-standard applications.

4. 10% Encapsulated Grade: Also available as a low-concentration encapsulated formulation with improved water solubility, suitable for aqueous-phase formulations.

5. Analytical Method: High-Performance Liquid Chromatography (HPLC). A Certificate of Analysis (COA) is provided with each shipment.

6. Quality Control: Heavy metal content and microbiological parameters are controlled to meet applicable cosmetic raw material standards.

Upon receipt of the goods, please promptly inspect the product appearance and quantity. Any damage, leakage, or shortage must be reported within 3 working days, accompanied by photographic evidence.

Quality-related claims may be submitted for independent testing within 15 days of receipt. Verification and resolution will be coordinated based on valid test reports.

Product deterioration resulting from improper storage or inappropriate formulation practices is not covered by the quality warranty.

We provide technical support and guidance on formulation incorporation, recommended addition levels, and ingredient compatibility. Customer inquiries are handled promptly. Quality issues attributable to non-human factors will be addressed through consultation and mutually agreed resolution. Compensation is available for confirmed lost shipments, ensuring reliable and consistent after-sales support.

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